1 and 2 are handlers, 3 sets stack, 7 is best cutter; force flick shown. Players must be spread out well and cut with smart direction and timing to avoid picks. Thrower will need to i/o semi-break their mark for the straight forward throw.
Here is a basic sequence showing how to re-establish positioning after moving the disc downfield in a Horizontal Offense. The basic premise with re-positioning is to typically have a Handler fill in the position left vacant by the Lane Cutter. The main goal is to maintain the overall positions where the player with the disc always has 2 options to reset the disc to another Handler, as well as 4 options downfield for continuation passes (2 primary and 2 secondary).
This play below describes how to play zone O against a standard 1-3-3 zone. The basic principles of zone O are dump and swing, crash the cup, dump swing etc... The focus is to pass a lot and expose any openings in the zone that can lead to quick throws up field. It's actually very easy to break most zones if the offensive players are aggressive and are comfortable with cutting into tight spaces. A key component of a good zone O is that the two wings (4,5) work together to create space. One player (5) can act as a decoy cut to draw in players while the other player (4) crashes to get a nice short pass.
This play is for teams that have highly skilled handlers who can pretty much throw against any force in any condition. The play is pretty basic at the core and starts out as a basic stack down the middle. From here the back lane cutters make 45 degree cuts to the front. Any good defensive team should be able to cover these. The play turns into an isolation play after one more player cuts deep and leaves one player isolated in the middle. Here it should not be too difficult for the cutter to get open for an easy score, a good handler can just throw to space with a bit of float, or maybe a hammer/scoober. It should be noted that any of the first cuts are good looks.