Vert Stack. Second Handler is in power position.
Simple man defense, no poaches anywhere. Tight man defense.
Second Handler (6) goes dishy but isn't open. Back of stack (5) fakes deep or out.
Back of stack (5) cuts on open side. Front of stack (1) cuts to negative space.
Primary option: Throw to front of stack (1) in negative space. Back of stack (4) is open deep.
Secondary Handler (6) has the option to run deep whenever he wants. Let's say the primary option isn't hit...
Secondary option: Hit the in-cut (5). 1 goes deep to cycle back into stack.
If front of stack (2) is open, throw to negative space. 1 cycles back in.
Now 6 is open for the break-side huck into negative space.